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Earlier in the season, many suggested Peyton Manning was through and should retire. He has since rebounded and will lead his Denver Broncos against the Carolina Panthers in Sunday's NFL Super Bowl.

Television debates have been a mainstay in presidential campaigns since 1976. Now, the GOP presidential front-runner is taking a big gamble just days before the Iowa caucuses.

The world's leading medical journals have a proposal that could transform medical science: Researchers would have to publicly share their clinical data to get their studies published.

Medicare compiles ratings of agencies' quality and of patients' perceptions. But the stars assigned by the government often don't align.

Former Secret Service agent Jonathan Wackrow spent five years on President Obama's detail. He talks to NPR's Rachel Martin about the problems that have led to the agency's current scandals.

The presidential candidate, who has emerged as the leading critic to Hillary Clinton, sat down with WAMU's Diane Rehm to talk about his campaign, policies and his chances.

What if you put all 7 billion humans into one city, a city as dense as New York, with its towers and skyscrapers? How big would that 7 billion-sized city be? As big as New Jersey? Texas? Bigger? Are cities protecting wild spaces on the planet? We try a little experiment to find out.

An exciting women's NCAA basketball tournament ended with a dominant win by UConn in Tuesday's final game. ESPN's Pablo Torre talks with host Michel Martin about the game and other sports news.

Ken Mehlman, the political director for the George W. Bush White House, compares the right to marry to other fundamental rights conservatives embrace. He rounded up a group of 131 prominent Republicans to sign a legal brief that's at odds with the House GOP leadership and the party's platform.

Jack Lew is known as a smart, unassuming budget wonk who has spent most of his career in government policy-making jobs. Lew, President Obama's nominee to be Treasury secretary, is expected to face questions about his management years at Citigroup before the government bailed out the banking giant.