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Vice President JD Vance faces a key moment in his career as he heads to Islamabad to negotiate the end of the U.S.-Israeli-led war in Iran.

In Oakland, a case is getting underway in which Elon Musk and Sam Altman will face off over the future of OpenAI, one of the world's most influential AI companies.

Labor groups say Arizona isn't moving fast enough to establish new protections for people whose work exposes them to the state's sizzling high temperatures.

President Trump has signed an executive order aimed at accelerating research and approval of psychedelics for treating mental health conditions, like depression, PTSD and addiction.

NPR's Mary Louise Kelly talks with A.E. Dick Howard, a drafter of Virginia's current constitution, about the state's impeachment policies, and how and why an elected official could be impeached.

NPR's Audie Cornish talks with Randy Capps, director of research for U.S. programs at the Migration Policy Institute, about the Democrats' proposal to cap the number of ICE detention beds.

California, Arizona and Nevada are facing big cuts in water from the Colorado river. Water managers' responses to the federal government's restrictions are now in.

As more states legalize marijuana, there's one group that's seen an increase in accidentally getting high: dogs. Discarded joints and THC edibles are just some of the ways dogs consume the drug.

NPR's Ailsa Chang speaks with Defector's Maitreyi Anantharaman about the NBA playoffs, which start next week with the play-in tournament to decide which teams get the last slots.

Denzel Washington takes on the title character in Joel Coen's Bard-based film, The Tragedy of Macbeth, with murder-minded Lady Macbeth played by Coen's wife, Frances McDormand.